The dystrophin-associated glycoprotein complex: what parts can you do without?
作者信息
Sweeney H L, Barton E R
机构信息
Department of Physiology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6085, USA.
出版信息
Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13464-6. doi: 10.1073/pnas.011510597.
Abstract
摘要
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本文引用的文献
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Adeno-associated virus vector carrying human minidystrophin genes effectively ameliorates muscular dystrophy in mdx mouse model.携带人微小肌营养不良蛋白基因的腺相关病毒载体可有效改善mdx小鼠模型中的肌营养不良症。
Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13714-9. doi: 10.1073/pnas.240335297.
2
Functional muscle ischemia in neuronal nitric oxide synthase-deficient skeletal muscle of children with Duchenne muscular dystrophy.杜兴氏肌营养不良症患儿神经元型一氧化氮合酶缺陷骨骼肌中的功能性肌肉缺血。
Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13818-23. doi: 10.1073/pnas.250379497.
3
Assembly of the dystrophin-associated protein complex does not require the dystrophin COOH-terminal domain.肌营养不良蛋白相关蛋白复合体的组装不需要肌营养不良蛋白的羧基末端结构域。
J Cell Biol. 2000 Sep 18;150(6):1399-410. doi: 10.1083/jcb.150.6.1399.
4
Absence of alpha-syntrophin leads to structurally aberrant neuromuscular synapses deficient in utrophin.α-肌养蛋白的缺失会导致结构异常的神经肌肉突触，其缺乏抗肌萎缩蛋白。
J Cell Biol. 2000 Sep 18;150(6):1385-98. doi: 10.1083/jcb.150.6.1385.
5
Rescue of skeletal muscles of gamma-sarcoglycan-deficient mice with adeno-associated virus-mediated gene transfer.腺相关病毒介导的基因转移对γ-肌聚糖缺乏小鼠骨骼肌的挽救作用。
Mol Ther. 2000 Feb;1(2):119-29. doi: 10.1006/mthe.1999.0019.
6
Trans-splicing vectors expand the utility of adeno-associated virus for gene therapy.反式剪接载体扩展了腺相关病毒在基因治疗中的应用。
Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6716-21. doi: 10.1073/pnas.97.12.6716.
7
Dystrophin and utrophin influence fiber type composition and post-synaptic membrane structure.肌营养不良蛋白和抗肌萎缩蛋白影响纤维类型组成和突触后膜结构。
Hum Mol Genet. 2000 May 22;9(9):1357-67. doi: 10.1093/hmg/9.9.1357.
8
Muscle degeneration without mechanical injury in sarcoglycan deficiency.肌聚糖缺乏症中无机械损伤的肌肉退化。
Proc Natl Acad Sci U S A. 1999 Sep 14;96(19):10723-8. doi: 10.1073/pnas.96.19.10723.
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Mutations in the Caenorhabditis elegans dystrophin-like gene dys-1 lead to hyperactivity and suggest a link with cholinergic transmission.秀丽隐杆线虫中与肌营养不良蛋白类似的基因dys-1发生突变会导致多动，并提示其与胆碱能传递存在关联。
Neurogenetics. 1998 Dec;2(1):61-72. doi: 10.1007/s100480050053.
10
alpha1-syntrophin gene disruption results in the absence of neuronal-type nitric-oxide synthase at the sarcolemma but does not induce muscle degeneration.α1-肌养蛋白基因缺失导致肌膜上缺乏神经元型一氧化氮合酶，但不会引发肌肉退化。
J Biol Chem. 1999 Jan 22;274(4):2193-200. doi: 10.1074/jbc.274.4.2193.
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