Baillargeon J, Borucki M J, Zepeda S, Jenson H B, Leach C T
Department of Pediatrics, University of Texas Health Science Center, San Antonio, TX 78284-7802, USA.
Clin Infect Dis. 2000 Dec;31(6):1476-81. doi: 10.1086/317478. Epub 2000 Nov 29.
Although the prevalence of human immunodeficiency virus (HIV) infection among prison inmates is reported to be high, little is known about anti-HIV treatment patterns in correctional institutions. The present study assessed antiretroviral prescribing patterns for 2360 Texas Department of Criminal Justice (TDCJ) inmates infected with HIV. In 1998, 66.8% of all TDCJ inmates infected with HIV who had CD4 lymphocyte counts < 500 cells/mm(3) were treated with highly active antiretroviral therapy (HAART). However, no substantial differences in the use of HAART were exhibited according to the sociodemographic factors under study. While the majority of inmates receiving HAART in 1998 were prescribed a combination of 2 nucleoside reverse transcriptase inhibitors (NRTIs) and 1 protease inhibitor, 11.2% were prescribed a combination of 2 NRTIs and 1 non-NRTI. In view of the elevated rate of HIV infection in correctional settings, it will be important to continue to document the pharmacotherapy patterns among prison inmates, both during and following incarceration.
虽然据报道监狱服刑人员中人类免疫缺陷病毒(HIV)感染率很高,但惩教机构中的抗HIV治疗模式却鲜为人知。本研究评估了2360名感染HIV的得克萨斯州刑事司法部(TDCJ)服刑人员的抗逆转录病毒药物处方模式。1998年,所有CD4淋巴细胞计数<500个细胞/mm³的TDCJ感染HIV服刑人员中,66.8%接受了高效抗逆转录病毒治疗(HAART)。然而,在所研究的社会人口统计学因素方面,HAART的使用没有表现出实质性差异。1998年,大多数接受HAART的服刑人员被开了2种核苷类逆转录酶抑制剂(NRTIs)和1种蛋白酶抑制剂的组合,11.2%的人被开了2种NRTIs和1种非NRTI的组合。鉴于惩教机构中HIV感染率较高,继续记录服刑人员在监禁期间及之后的药物治疗模式将很重要。