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西班牙艾滋病毒感染囚犯对抗逆转录病毒疗法的依从性

Adherence to antiretroviral therapy among HIV-infected prison inmates (Spain).

作者信息

Soto Blanco José M, Pérez Isabel Ruiz, March Joan C

机构信息

Hospital Universitario San Cecilio, Granada, Spain.

出版信息

Int J STD AIDS. 2005 Feb;16(2):133-8. doi: 10.1258/0956462053057503.

Abstract

This cross-sectional study was carried out in two Spanish prisons. A group of 177 HIV-infected prison inmates were interviewed. Standardized personal interviews using a structured questionnaire were conducted to assess sociodemographic features and prison setting characteristics, clinical variables, social support and drug consumption. A simplified four-item questionnaire for self-reported adherence was used. A total of 24.3% were non-adherent. Predictors of non-adherence in the multivariate analysis included poor or lack of ability to follow the prescribed treatment regimen, no visits in a month, anxious and/or depressed mood, difficulty in taking medication, receiving methadone treatment, cannabis consumption and robbery as the reason for imprisonment. Adherence to antiretroviral therapy was higher than in the wider community. However, other variables related to the correctional setting, such as assignments within the facility, adaptability of the prison system to authorize the cell being opened in the event of missed medication, or legal situation had no effect on adherence for inmates with HIV disease.

摘要

这项横断面研究在西班牙的两所监狱中开展。对177名感染艾滋病毒的监狱囚犯进行了访谈。采用结构化问卷进行标准化个人访谈,以评估社会人口学特征、监狱环境特征、临床变量、社会支持和药物使用情况。使用了一份简化的四项自我报告依从性问卷。共有24.3%的人依从性差。多变量分析中依从性差的预测因素包括遵循规定治疗方案的能力差或缺乏该能力、一个月内无探访、焦虑和/或抑郁情绪、服药困难、接受美沙酮治疗、吸食大麻以及因抢劫入狱。抗逆转录病毒疗法的依从性高于更广泛的社区。然而,与惩教环境相关的其他变量,如监狱内的任务分配、监狱系统在错过服药时批准打开牢房的适应性或法律状况,对感染艾滋病毒疾病的囚犯的依从性没有影响。

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