Gieffers J, Solbach W, Maass M
Institute of Medical Microbiology and Hygiene, Medical University of Lübeck, D-23538 Lübeck, Germany.
Clin Infect Dis. 2000 Dec;31(6):1515-6. doi: 10.1086/317505.
Chlamydia pneumoniae is detectable in the blood vessels of patients suffering from arteriosclerosis. Risk for arteriosclerosis is modulated by the apolipoprotein E (apoE) allele. We assessed the significance of the apoE genotype as a risk factor for vascular C. pneumoniae infection by determining the genotype of 30 coronary heart disease patients with PCR-proven C. pneumoniae infection of coronary artery tissue. The apoE genotype is not distinctly associated with an increased risk for vascular C. pneumoniae infection.
在患有动脉硬化的患者血管中可检测到肺炎衣原体。动脉硬化风险受载脂蛋白E（apoE）等位基因调节。我们通过对30例经PCR证实冠状动脉组织感染肺炎衣原体的冠心病患者进行基因分型，评估apoE基因型作为血管肺炎衣原体感染风险因素的意义。apoE基因型与血管肺炎衣原体感染风险增加并无明显关联。
