Martínez-Ruiz E, Ortega C, Calduch L, Molina I, Montesinos E, Revert A, Cardá C, Navarro V, Jordá E
Department of Dermatology, Hospital Clínico Universitario, Valencia, Spain.
Dermatology. 2000;201(3):252-4. doi: 10.1159/000018498.
A 41-year-old male developed a generalized drug eruption following sulfamide therapy, with progressive albino-like generalized cutaneous depigmentation. Electron microscopy showed the absence of melanocytes, and clear cells with Langerhans cell characteristics were seen along the basal layer. The present case constitutes a unique reaction to sulfamides not previously reported in the literature.
一名41岁男性在接受磺胺治疗后出现全身性药疹，并伴有进行性白化病样全身性皮肤色素脱失。电子显微镜检查显示黑素细胞缺失，在基底层可见具有朗格汉斯细胞特征的透明细胞。本病例构成了一种对磺胺类药物的独特反应，此前文献中未见报道。
