Rosenberg FM, Chan A, Lichtenstein SV, McManus BM
Department of Pathology and Laboratory Medicine, St. Paul's Hospital, 1081 Burrard Street, Vancouver, British Columbia, Canada V6Z 1Y6.
Curr Treat Options Cardiovasc Med. 1999 Oct;1(3):243-252. doi: 10.1007/s11936-999-0040-6.
Surgical resection is usually the only form of curative therapy available for primary cardiac neoplasms. Benign tumors can often be completely removed with few complications and a low mortality rate, but complete resection is possible for fewer than half of primary malignant tumors. Radiation therapy plays an adjunct and palliative role in treatment. The outcome of chemotherapy, the dominant treatment method, is poor. Sarcomas are inherently chemoresistant and show a response rate of less than 50%. Lymphomas present late and respond poorly. Cardiectomy and cardiac transplantation may cure unresectable benign cardiac tumors or, rarely, malignant ones.
手术切除通常是原发性心脏肿瘤唯一可用的治愈性治疗方式。良性肿瘤通常可以完全切除，并发症少且死亡率低，但原发性恶性肿瘤中能够完全切除的不到半数。放射治疗在治疗中起辅助和姑息作用。作为主要治疗方法的化疗效果不佳。肉瘤本质上对化疗耐药，缓解率低于50%。淋巴瘤出现较晚且反应较差。心脏切除术和心脏移植可能治愈无法切除的良性心脏肿瘤，或很少情况下的恶性肿瘤。
