Tetsuka Syuichi, Ikeguchi Kunihiko
Department of Neurology, Hospital of International University of Health and Welfare, 537-3 Iguchi, Nasushiobara, Tochigi 329-2763, Japan.
Jichi Medical University Station Brain Clinic, 3-2-2 Idaimae, Shimotsuke, Tochigi 329-0403, Japan.
Case Rep Med. 2015;2015:151802. doi: 10.1155/2015/151802. Epub 2015 Apr 14.
A 21-year-old woman developed left hemiparesis during work and was hospitalized. Her National Institutes of Health Stroke Scale score was 4. Hyperintense areas in the left basal ganglia, corona radiata, and cortex of the temporal lobe were found by brain diffusion-weighted magnetic resonance imaging, indicating acute cerebral infarction. Echocardiography showed a giant mass of diameter 7 × 4 cm in the left atrium. Therefore, she was diagnosed with cerebral embolism due to a left atrial myxoma. Currently, thrombolytic therapy may continue to be effective because the embolic source may be composed of tumor tissue itself. In case of atrial myxoma, we considered that the use of tPA as emergency treatment in all patients with infarction by atrial myxoma may be questioned. Thus, cardiac tumor extraction was performed the next day after hospitalization without thrombolytic therapy. The excised myxoma measured 7 × 6 × 4 cm. The patient recovered and her neurological symptoms also improved. Furthermore, her National Institutes of Health Stroke Scale score improved to 0. Thirteen days after admission, the patient was discharged from our hospital. Cardiac myxoma is often associated with a high risk of embolic episodes, which emphasizes the need for prompt surgical excision as soon as the diagnosis is confirmed.
一名21岁女性在工作期间出现左侧偏瘫并住院。她的美国国立卫生研究院卒中量表评分为4分。脑部弥散加权磁共振成像发现左侧基底节、放射冠和颞叶皮质有高信号区,提示急性脑梗死。超声心动图显示左心房有一个直径7×4 cm的巨大肿块。因此,她被诊断为左心房黏液瘤所致的脑栓塞。目前,溶栓治疗可能仍然有效,因为栓子来源可能是肿瘤组织本身。对于心房黏液瘤,我们认为对所有因心房黏液瘤导致梗死的患者使用tPA作为紧急治疗可能会受到质疑。因此,住院次日未进行溶栓治疗即进行了心脏肿瘤切除术。切除的黏液瘤大小为7×6×4 cm。患者康复,神经症状也有所改善。此外,她的美国国立卫生研究院卒中量表评分提高到了0分。入院13天后,患者从我院出院。心脏黏液瘤常伴有较高的栓塞发作风险,这强调了一旦确诊就需要立即进行手术切除。