Berinstein D M, Hassan T S, Williams G A, Margherio R R, Ruby A J, Garretson B R
Associated Retinal Consultants, PC, Department of Ophthalmology, Beaumont Eye Institute, Royal Oak, Michigan, USA.
Ophthalmology. 2000 Dec;107(12):2233-9. doi: 10.1016/s0161-6420(00)00417-6.
To evaluate the visual and anatomic results of surgically repaired macular holes in eyes with intermediate or large-sized macular drusen.
Retrospective noncomparative case series.
Thirty-four eyes of 32 patients undergoing macular hole surgery with preoperative intermediate or large-sized macular drusen as defined by the Age-Related Eye Disease Study (AREDS).
Pars plana vitrectomy for standard macular hole repair performed by multiple surgeons.
Visual acuity, anatomic hole closure.
Initial hole closure failed in 8 eyes (24%) overall, 5 of 28 eyes (18%) with AREDS category 2 drusen and 3 of 6 eyes (50%) with category 3 drusen (P = 0.1263). Final macular hole closure was seen in 93% of category 2 and 67% of category 3 eyes (P = 0.1347). Mean final visual acuity was 20/60 overall, 20/60 for category 2, and 20/50 for category 3 eyes.
A trend of reduced initial macular hole closure was seen in eyes with significant macular drusen. Reoperation improved closure rates. If closure was accomplished, visual outcomes were excellent.
评估手术修复伴有中度或大型黄斑玻璃膜疣的眼中黄斑裂孔的视力及解剖学结果。
回顾性非对照病例系列。
32例患者的34只眼，这些患者接受了黄斑裂孔手术，术前存在年龄相关性眼病研究（AREDS）定义的中度或大型黄斑玻璃膜疣。
由多名外科医生进行标准黄斑裂孔修复的玻璃体切除术。
视力、解剖学上的裂孔闭合情况。
总体上8只眼（24%）初次裂孔闭合失败，28只患有AREDS 2级玻璃膜疣的眼中有5只（18%），6只患有3级玻璃膜疣的眼中有3只（50%）（P = 0.1263）。93%的2级眼和67%的3级眼最终黄斑裂孔闭合（P = 0.1347）。总体平均最终视力为20/60，2级眼为20/60，3级眼为20/50。
在伴有明显黄斑玻璃膜疣的眼中，初次黄斑裂孔闭合率有降低趋势。再次手术提高了闭合率。如果实现了闭合，视力结果良好。
