Oh Ha Na, Lee Joo Eun, Kim Hyun Woong, Yang Jae Wook, Yun Il Han
Department of Ophthalmology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.
Clin Ophthalmol. 2012;6:1287-91. doi: 10.2147/OPTH.S33650. Epub 2012 Aug 10.
To report on a case that developed an atypical form of occult choroidal neovascularization (CNV) after successful macular hole surgery.
Visual acuity change, color fundus photographs, fluorescein and indocyanine green angiograms, and optical coherence tomography results were compared throughout the follow-up duration.
A 64-year-old woman with a macular hole in the right eye and drusen in both eyes underwent pars plana vitrectomy, internal limiting membrane peeling, and gas tamponade. One month after the operation she developed occult CNV, in which pigment epithelial detachment and fine retinal pigment epithelial (RPE) layer wrinkles were observed under the completely sealed macular hole. After 3-monthly intravitreal injections of ranibizumab, the lesion did not change significantly.
CNV can develop after otherwise successful macular hole surgery, especially in patients with pre-existing aging changes in the macula, such as drusen. Care should be taken in such patients, to prevent the development of CNV after macular hole surgery.
报告一例黄斑裂孔手术成功后发生非典型隐匿性脉络膜新生血管（CNV）的病例。
在整个随访期间比较视力变化、彩色眼底照片、荧光素和吲哚菁绿血管造影以及光学相干断层扫描结果。
一名64岁女性，右眼有黄斑裂孔，双眼有玻璃膜疣，接受了玻璃体切割术、内界膜剥除术和气体填塞。术后1个月，她出现了隐匿性CNV，在完全封闭的黄斑裂孔下方观察到色素上皮脱离和视网膜色素上皮（RPE）层细微皱纹。在每月一次玻璃体内注射雷珠单抗3个月后，病变无明显变化。
黄斑裂孔手术成功后仍可发生CNV，尤其是在黄斑区已有老化改变（如玻璃膜疣）的患者中。对此类患者应予以关注，以预防黄斑裂孔手术后CNV的发生。
