Gorisek B, Zegura B, Kavalar R, But I, Krajnc I
Clinical Department of Gynecology and Perinatology, Maribor Teaching Hospital, Slovenia.
Wien Klin Wochenschr. 2000 Oct 13;112(19):855-8.
Since 1872, 40 cases of ectopic mammary gland tissue in the vulva have been reported in the literature. Out of these, 12 had a primary cancer in the ectopic breast tissue. Seven metastases of an orthotopic breast cancer have been found in this location. We are presenting the 20th case of cancerous breast tissue in the vulva whom we classified as the 13th case of primary cancer based on clinical and histopathological criteria of primary and metastatic malignant disease. Because of the advanced age of the patient, wide local excision followed by adjuvant hormonal therapy was opted for. Nineteen months after surgery, there is no evidence of recurrent disease. Due to the rarity of this entity, its management presents therapeutic dilemmas, and variable treatment strategies are being found in the literature. In our opinion, the same basic principles used for treatment of cancers of the orthotopic breast should be applied in ectopic breast carcinoma.
自1872年以来，文献中已报道了40例外阴异位乳腺组织病例。其中，12例异位乳腺组织发生原发性癌。在此部位发现了7例原位乳腺癌转移。我们现报告第20例外阴癌性乳腺组织病例，根据原发性和转移性恶性疾病的临床及组织病理学标准，我们将其归类为第13例原发性癌。由于患者年龄较大，选择了广泛局部切除并辅以辅助激素治疗。术后19个月，无疾病复发迹象。由于该实体罕见，其治疗存在治疗困境，文献中也有不同的治疗策略。我们认为，原位乳腺癌的相同基本治疗原则应适用于异位乳腺癌。
