Suppr超能文献

[主动脉根部重建手术]

[Reconstructive surgery of the aortic root].

作者信息

Graeter T, Kindermann M, Fries R, Schäfers H J

机构信息

Abteilung für Thorax- und Herz-Gefässchirurgie Universitätskliniken des Saarlandes, Homburg/Saar.

出版信息

Z Kardiol. 2000;89 Suppl 7:107-11.

Abstract

Surgical treatment of proximal aortic disease traditionally consists of composite replacement of valve and aorta. Recent reconstructive procedures on the aortic root allow for treatment of aortic dilatation and concomitant aortic valve regurgitation without the associated disadvantages of mechanical heart valves. From 10/95 to 09/99 we treated 84 patients for regurgitation of the aortic valve and dilatation of the aortic root. Valve preserving replacement of the root consisted of root remodeling (n = 68) or reimplantation of the aortic valve (n = 16). Operative mortality in valve-preserving surgery was not elevated compared to overall results of proximal aortic replacement (3.6% vs 5.6%); this applied to elective procedures (1.8% vs 2.3%) as well as emergency operations (9.3% vs 16.3%). Initial aortic valve function was adequate in all cases. Actuarial freedom from regurgitation grade II or higher was 98% after root remodeling and 92% after valve reimplantation. Freedom from reoperation at two years was 96% in remodeling and 100% in valve reimplantation. Hemodynamic function of the reconstructed valve was investigated in 17 patients under conditions of rest and exercise. These were compared to 9 patients with a mechanical composite valve. Patients with reconstructed valves had almost physiologic gradients during rest and exercise. These gradients were thus significantly lower than the increased gradients of patients after composite replacement. Application of reconstructive procedures to the aortic root allows for restoration of aortic valve function in the majority of patients. Disadvantages of heart valve prostheses can be avoided, and the hemodynamic performance of the reconstructed valve appears almost physiologic.

摘要

传统上,近端主动脉疾病的外科治疗包括瓣膜和主动脉的复合置换。最近针对主动脉根部的重建手术能够治疗主动脉扩张以及伴随的主动脉瓣反流,且不存在机械心脏瓣膜相关的缺点。从1995年10月至1999年9月,我们治疗了84例主动脉瓣反流和主动脉根部扩张的患者。保留瓣膜的根部置换包括根部重塑(n = 68)或主动脉瓣再植入(n = 16)。与近端主动脉置换的总体结果相比,保留瓣膜手术的手术死亡率并未升高(3.6% 对5.6%);这适用于择期手术(1.8% 对2.3%)以及急诊手术(9.3% 对16.3%)。所有病例术后初始主动脉瓣功能均良好。根部重塑后无II级或更高等级反流的精算生存率为98%,瓣膜再植入后为92%。两年时无需再次手术的生存率,根部重塑为96%,瓣膜再植入为100%。对17例患者在静息和运动状态下研究了重建瓣膜的血流动力学功能,并与9例使用机械复合瓣膜的患者进行比较。重建瓣膜的患者在静息和运动时具有几乎生理性的压力阶差。因此,这些压力阶差显著低于复合置换术后患者升高的压力阶差。对主动脉根部应用重建手术能够使大多数患者的主动脉瓣功能得以恢复。心脏瓣膜假体的缺点可以避免,且重建瓣膜的血流动力学性能几乎呈生理性。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验