Redouté J, Stoléru S, Grégoire M C, Costes N, Cinotti L, Lavenne F, Le Bars D, Forest M G, Pujol J F
Centre d'Exploration et de Recherche Médicale par Emission de Positons (CERMEP), Lyon, France.
Hum Brain Mapp. 2000 Nov;11(3):162-77. doi: 10.1002/1097-0193(200011)11:3<162::aid-hbm30>3.0.co;2-a.
Despite its critical sociobiological importance, the brain processing of visual sexual stimuli has not been characterized precisely in human beings. We used Positron Emission Tomography (PET) to investigate responses of regional cerebral blood flow (rCBF) in nine healthy males presented with visual sexual stimuli of graded intensity. Statistical Parametric Mapping was used to locate brain regions whose activation was associated with the presentation of the sexual stimuli and was correlated with markers of sexual arousal. The claustrum, a region whose function had been unclear, displayed one of the highest activations. Additionally, activations were recorded in paralimbic areas (anterior cingulate gyrus, orbito-frontal cortex), in the striatum (head of caudate nucleus, putamen), and in the posterior hypothalamus. By contrast, decreased rCBF was observed in several temporal areas. Based on these results, we propose a model of the brain processes mediating the cognitive, emotional, motivational, and autonomic components of human male sexual arousal.
尽管视觉性刺激在社会生物学中具有至关重要的意义，但人类大脑对其的处理过程尚未得到精确描述。我们利用正电子发射断层扫描（PET）技术，研究了九名健康男性在面对不同强度视觉性刺激时局部脑血流（rCBF）的反应。采用统计参数映射法来定位那些激活与性刺激呈现相关且与性唤起指标相关的脑区。屏状核，一个功能一直不明的区域，表现出最高的激活之一。此外，在边缘旁区域（前扣带回、眶额皮质）、纹状体（尾状核头部、壳核）以及下丘脑后部均记录到激活。相比之下，在几个颞叶区域观察到rCBF减少。基于这些结果，我们提出了一个介导人类男性性唤起的认知、情感、动机和自主成分的大脑过程模型。
