Jennings P B, McCarthy M K, Plymate S R, Wettlaufer J N
Fertil Steril. 1975 Jan;26(1):53-6. doi: 10.1016/s0015-0282(16)40874-5.
Thirty-two men undergoing vasectomy were studied for one year to determine presence of HL-A antibodies after surgery. Blood samples were taken prior to vasectomy and at three, six, nine, and 12 months following surgery. Twenty-six men showed no increase in antibody activity during the study when their sera were matched against a 25-member typed lymphocyte donor panel. Sera of two men showed a definite increase in positive reactions, six to 12 months after surgery. The sera of four men showed slight increases in reactivity between three and 12 months after vasectomy. The serum of one man showed a single positive reaction against his own lymphocytes three months after surgery, but no positive reactivity against the lymphocyte donor panel. These studies suggest that HL-A antibodies are not regularly formed as a result of standard vasectomy procedures, but that further long-term evaluation of vasectomized patients may be needed to make definite conclusions.
对32名接受输精管切除术的男性进行了为期一年的研究，以确定术后HL-A抗体的存在情况。在输精管切除术之前以及术后3个月、6个月、9个月和12个月采集血样。当将26名男性的血清与一个由25名分型淋巴细胞供体组成的小组进行匹配时，在研究期间他们的抗体活性没有增加。两名男性的血清在术后6至12个月出现阳性反应明显增加。四名男性的血清在输精管切除术后3至12个月反应性略有增加。一名男性的血清在术后3个月对其自身淋巴细胞出现单次阳性反应，但对淋巴细胞供体小组没有阳性反应。这些研究表明，标准输精管切除手术不会经常导致HL-A抗体的形成，但可能需要对输精管切除患者进行进一步的长期评估才能得出明确结论。
