输精管切除术后的免疫学观察。

Immunological observations following vasectomy.

作者信息

Choi Y J, Reiner L, Ney C

出版信息

Experientia. 1979 Sep 15;35(9):1243-4. doi: 10.1007/BF01963315.

DOI:10.1007/BF01963315

Abstract

Lymphocytotoxic antibodies (LCA) against panels of normal lymphocytes and leukemic B-cells were demonstrated in vasectomized men. Since vasectomy is known to induce antibody formation to spermatozoa, the demonstration of these lymphocytotoxic antibodies may be related to antigenic constituents of spermatozoa such as HLA or B-cell alloantigens. Long term follow-up is needed to clarify the clinical significance of these antibodies.

摘要

在接受输精管切除术的男性中，检测到针对正常淋巴细胞和白血病B细胞的淋巴细胞毒性抗体（LCA）。由于已知输精管切除术会诱导机体产生抗精子抗体，这些淋巴细胞毒性抗体的出现可能与精子的抗原成分有关，如人类白细胞抗原（HLA）或B细胞同种异体抗原。需要进行长期随访以阐明这些抗体的临床意义。