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BALB/c小鼠在莫里斯水迷宫实验中的表现不算差。

BALB/c mice are not so bad in the Morris water maze.

作者信息

Chapillon P, Debouzie A

机构信息

UPRES EA 1780 Laboratoire de Neurobiologie de l'Apprentissage, Faculté des Sciences, Université de Rouen, F-76821 Cedex, Mont Saint Aignan, France.

出版信息

Behav Brain Res. 2000 Dec 20;117(1-2):115-8. doi: 10.1016/s0166-4328(00)00292-8.

DOI:10.1016/s0166-4328(00)00292-8
PMID:11099764
Abstract

We compared the learning performances of BALB/c mice subjected to the Morris water spatial task under two different lighting conditions. In the first one, the experimental room was lit by neon tubes (direct and bright illumination) and in the second one by a halogen lamp directed to the roof (diffuse illumination). The scores of BALB/c mice in the diffuse illumination condition clearly demonstrated that these mice could learn to escape to a hidden platform while they could not under direct illumination condition. Moreover, they were able to acquire the task by means of spatial cues. These results are interpreted in terms of a decrease of anxiety levels.

摘要

我们比较了在两种不同光照条件下进行莫里斯水空间任务的BALB/c小鼠的学习表现。在第一种条件下,实验室由霓虹灯管照明(直接明亮照明),在第二种条件下,由指向屋顶的卤素灯照明(漫射照明)。BALB/c小鼠在漫射照明条件下的得分清楚地表明,这些小鼠能够学会逃向隐藏平台,而在直接照明条件下则不能。此外,它们能够通过空间线索来掌握任务。这些结果可从焦虑水平降低的角度来解释。

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