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腹腔镜下肝段亚切除术治疗肝硬化合并肝细胞癌

Laparoscopic subsegmentectomy for hepatocellular carcinoma with cirrhosis.

作者信息

Ker C G, Chen H Y, Juan C C, Chang W S, Tsai C Y, Lo H W, Yau M T

机构信息

Division of HBP Surgery, Yuan's General Hospital, Kaohsiung, Taiwan.

出版信息

Hepatogastroenterology. 2000 Sep-Oct;47(35):1260-3.

Abstract

BACKGROUND/AIMS: Laparoscopic liver resection is feasible for both benign and malignant disease with today's laparoscopic techniques and technology. Location of the tumor at the edge of segment 3, 4, 5, or 6 of our patients makes them an ideal candidate for laparoscopic resection.

METHODOLOGY

There were 9 patients who underwent laparoscopic subsegmentectomy for hepatocellular carcinoma with cirrhosis. They were classified as Child A in 6 and B in 3 patients. Hepatitis B was found in 5 and Hepatitis C in 4 cases. Preoperative diagnosis of hepatocellular carcinoma was completed in 7 and definitive histologic diagnosis from frozen section in 2 cases. All 9 patients underwent subsegmentectomy and removal of the tumor with non-tumor cirrhotic liver with a distance of 10 mm at the least margin. Laparoscopic ultrasound allows exact localization of lesions and achievement of adequate resection margin.

RESULTS

Those patients resumed a full diet on the 2nd-3rd day after the operation and were discharged home on day 4-7 with no complications but one had prolonging discharge due to ascitis from a drainage tube. Finally, the ascitis was controlled by medications for 1 week. All patients had high postoperative satisfaction.

CONCLUSIONS

Laparoscopic liver resection is a procedure of significant risk and technically demanding. Therefore, it should be performed only by experienced liver surgeons with a high level of laparoscopic skill and in the carefully selected patient.

摘要

背景/目的:凭借当今的腹腔镜技术和工艺,腹腔镜肝切除术对于良性和恶性疾病均可行。我们的患者肿瘤位于第3、4、5或6段边缘,这使他们成为腹腔镜切除术的理想候选者。

方法

有9例肝硬化肝细胞癌患者接受了腹腔镜亚段切除术。其中6例为Child A级,3例为Child B级。5例发现乙肝,4例发现丙肝。7例完成了肝细胞癌的术前诊断,2例通过冰冻切片获得了明确的组织学诊断。所有9例患者均接受了亚段切除术,并切除了肿瘤及距肿瘤至少10毫米的无肿瘤肝硬化肝组织。腹腔镜超声可实现病变的精确定位并获得足够的切缘。

结果

这些患者术后第2 - 3天恢复正常饮食,第4 - 7天出院,无并发症,但有1例因引流管导致的腹水而延长了出院时间。最后,腹水通过药物治疗1周得到控制。所有患者术后满意度都很高。

结论

腹腔镜肝切除术是一种风险较大且技术要求较高的手术。因此,该手术应由具备高水平腹腔镜技术的经验丰富的肝脏外科医生在精心挑选的患者中进行。

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