Jodka P G, Heard S O
School of Medicine, Tufts University, Boston, MA 02111, USA.
Int Anesthesiol Clin. 2000 Fall;38(4):1-29. doi: 10.1097/00004311-200010000-00003.
Sepsis, severe sepsis, and septic shock represent the spectrum of physiological response to a variety of infecting pathogens. Multiple-organ dysfunction may result from widespread activation of inflammatory and antiinflammatory mechanisms. Intensive multiorgan support, effective antibiotic therapy, and eradication of the inciting source remain the cornerstones in the care of septic patients. Perioperative planning and management need to ensure the continuation of such care in addition to providing for the requirements of the given surgical procedure.
脓毒症、严重脓毒症和感染性休克代表了机体对多种感染病原体的一系列生理反应。炎症和抗炎机制的广泛激活可能导致多器官功能障碍。强化的多器官支持、有效的抗生素治疗以及消除诱发因素仍然是脓毒症患者治疗的基石。围手术期规划和管理除了要满足特定手术的需求外，还需确保此类治疗的持续进行。
