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肌肉浸润性膀胱癌患者的外照射和后装组织间放疗下的器官保留

Organ preservation by external beam and afterloading interstitial radiation in patients with muscle infiltrating bladder cancer.

作者信息

Wijnmaalen A, Boeken Kruger C C

机构信息

Department of Radiation Oncology, University Hospital Rotterdam-Daniel, Rotterdam, The Netherlands.

出版信息

Semin Urol Oncol. 2000 Nov;18(4):308-12.

PMID:11101095
Abstract

In several European cancer centers, the combination of external beam and interstitial radiotherapy with the aim of bladder preservation is standard treatment in a selected group of patients with muscle-infiltrating bladder cancer. Three case reports are presented. The published local control rates at 5 years vary from 64% to 88% and the 5-year overall and disease-free survival range from 47% to 66% and from 62% to 81%, respectively. It is concluded that this approach is successful in preserving the bladder. Conditions for good results are careful selection of patients, excellent cooperation between urologist and radiation oncologist, and modern brachytherapy facilities.

摘要

在几个欧洲癌症中心,对于选定的一组肌肉浸润性膀胱癌患者,以保留膀胱为目的的外照射和组织间放疗联合是标准治疗方法。本文介绍了3例病例报告。已发表的5年局部控制率在64%至88%之间,5年总生存率和无病生存率分别在47%至66%以及62%至81%之间。得出的结论是,这种方法在保留膀胱方面是成功的。取得良好效果的条件是仔细挑选患者、泌尿外科医生与放射肿瘤学家之间的密切合作以及现代化的近距离放疗设备。

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Semin Urol Oncol. 2000 Nov;18(4):308-12.
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