Gérard J P, De Laroche G, Ardiet J M, Romestaing P, Auque J R
J Urol (Paris). 1985;91(3):139-44.
Sixty patients with infiltrating bladder cancer were treated by partial cystectomy and iridium radiotherapy between 1977 and 1982. Actuarial 5-year survival was 90% for pT1, 51% for pT2 and 34% for pT3, bladder treatment being unsuccessful in 6 cases (11%). Long-term functional results were satisfactory. Iridium provides better radioprotection than radium and stricter dosage can be established. This conservative treatment for infiltrating bladder cancer is particularly indicated for pT1 and pT2 tumors, as single lesions and with a largest diameter not exceeding 4 cm. Results are better in cases with tumors of the mobile portion of bladder, the 5-year survival in these selected cases being 85% with a minimum of sequelae. This treatment may be used, generally combined with external radiotherapy, for tumors infiltrating deeply into muscle and more distant tissues.
1977年至1982年间，60例浸润性膀胱癌患者接受了膀胱部分切除术和铱放疗。pT1期患者的5年精算生存率为90%，pT2期为51%，pT3期为34%，6例（11%）膀胱治疗失败。长期功能结果令人满意。铱比镭提供更好的放射防护，并且可以确定更严格的剂量。这种浸润性膀胱癌的保守治疗特别适用于pT1和pT2期肿瘤，为单发病变且最大直径不超过4厘米。膀胱活动部肿瘤患者的治疗效果更好，这些特定病例的5年生存率为85%，后遗症最少。这种治疗方法通常与外照射放疗联合使用，用于肿瘤深度浸润肌肉和更远组织的情况。
