叠氮化钠对黑腹果蝇的诱变效应。

Mutagenic effects of sodium azide in Drosophila melanogaster.

作者信息

Kamra O P, Gollapudi B

出版信息

Mutat Res. 1979 Apr;66(4):381-4. doi: 10.1016/0165-1218(79)90049-1.

Abstract

The mutagenic effects of sodium azide (NaN3) were studied at low pH in male Drosophila melanogaster using the sex-linked recessive-lethal test. No significant increase in the mutation frequency was observed after abdominal injection of azide solutions buffered at either pH 3.8 OR 4.6. However, a weak mutagenic effect was noticed in the flies fed for 3 days on 0.1 mM azide (pH 4.6) solution.

摘要

利用性连锁隐性致死试验，研究了低pH条件下叠氮化钠（NaN₃）对雄性黑腹果蝇的诱变作用。腹腔注射pH值为3.8或4.6缓冲的叠氮溶液后，未观察到突变频率显著增加。然而，在以0.1 mM叠氮（pH 4.6）溶液喂养3天的果蝇中发现了微弱的诱变作用。