Mitchell E, Krous H F, Donald T, Byard R W
Forensic Science Centre and Department of Pathology, University of Adelaide, Australia.
Am J Forensic Med Pathol. 2000 Dec;21(4):395-400. doi: 10.1097/00000433-200012000-00020.
Retrospective analysis of autopsy findings in 60 infants who had been found unexpectedly dead in their cribs or beds in South Australia from 1994 to 1998 was undertaken to determine the diagnostic usefulness of individual stages in the postmortem investigation. Positive findings occurred in 2 of 43 scene examinations (3%), 2 of 60 external examinations (3%), 2 of 11 radiologic examinations (18%), 8 of 60 internal examinations (13%), 7 of 60 histologic examinations (12%), and 3 of 58 microbiologic examinations (5%). No positive findings were detected on toxicologic screening. Not every case underwent each diagnostic step. This gave alternative diagnoses to sudden infant death syndrome (SIDS) in 15 cases (25%). This study demonstrates an increase in the percentage of cases of unexpected infant death due to causes other than SIDS; it also shows the diagnostic yield of individual stages in the postmortem evaluation of such cases. Negative findings were important in giving validity to the diagnosis in the 45 cases that were ultimately designated as SIDS.
对1994年至1998年在南澳大利亚州婴儿床或床上意外死亡的60名婴儿的尸检结果进行回顾性分析，以确定尸检调查各个阶段的诊断效用。43次现场检查中有2次（3%）发现阳性结果，60次外部检查中有2次（3%），11次放射学检查中有2次（18%），60次内部检查中有8次（13%），60次组织学检查中有7次（12%），58次微生物学检查中有3次（5%）。毒理学筛查未发现阳性结果。并非每个病例都进行了每个诊断步骤。这为15例（25%）婴儿猝死综合征（SIDS）提供了其他诊断。本研究表明，非SIDS原因导致的意外婴儿死亡病例百分比有所增加；它还显示了此类病例尸检评估中各个阶段的诊断率。阴性结果对于最终被认定为SIDS的45例病例的诊断有效性很重要。
