正常和病理状态下的天然催化抗体（抗体酶）
Natural catalytic antibodies (abzymes) in normalcy and pathology.
作者信息
Nevinsky G A, Kanyshkova T G, Buneva V N
机构信息
Novosibirsk Institute of Bioorganic Chemistry, Siberian Division of the Russian Academy of Sciences, Novosibirsk, 630090, Russia.
出版信息
Biochemistry (Mosc). 2000 Nov;65(11):1245-55.
PMID:11112840
Abstract
This review summarizes literature data on natural abzymes. Peculiar features of their functioning and substrate specificity are considered in comparison with traditional enzymes. Working hypotheses on the possible biological roles of natural abzymes in autoimmune processes and diseases accompanied by disorders of immune status are analyzed.
摘要
本综述总结了关于天然抗体酶的文献数据。与传统酶相比，考虑了它们功能的独特特征和底物特异性。分析了关于天然抗体酶在自身免疫过程和伴有免疫状态紊乱的疾病中可能的生物学作用的工作假说。
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