Dominici A, Mondaini N, Nesi G, Travaglini F, Di Cello V, Rizzo M
Department of Urology, University of Florence, Italy.
Urol Int. 2000;65(4):229-31. doi: 10.1159/000064886.
Primary sarcomas of the kidney are rare, accounting for 1-3% of all renal malignancies. We describe an unusual case of renal leiomyosarcoma in a 41-year-old white woman who presented with a large smooth mass, which was mobile to the overlying structures and which occupied the right hypochondria and flank. Radical nephrectomy was carried out and the patient is well, without symptoms of relapse, 1 year after surgery. Leiomyosarcomas of the kidney have an aggressive and rapidly progressive natural history, with 5-year survival rates of 29-36%. Size <5 cm, low histological grade, absence of lymph node metastases and radical surgical treatment are all associated with a better prognosis. Irradiation and chemotherapy do not appear to alter the clinical course.
原发性肾肉瘤很罕见，占所有肾恶性肿瘤的1% - 3%。我们描述了一例不同寻常的肾平滑肌肉瘤病例，患者为一名41岁的白人女性，其表现为一个巨大的光滑肿块，可活动至上方结构，占据右季肋部和侧腹。患者接受了根治性肾切除术，术后1年情况良好，无复发症状。肾平滑肌肉瘤具有侵袭性且自然病程进展迅速，5年生存率为29% - 36%。肿瘤大小<5 cm、组织学分级低、无淋巴结转移以及根治性手术治疗均与较好的预后相关。放疗和化疗似乎不会改变临床病程。
