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3家管理式医疗组织中儿童哮喘的药物治疗与使用情况。儿科哮喘护理患者结局研究团队。

Asthma pharmacotherapy and utilization by children in 3 managed care organizations. The Pediatric Asthma Care Patient Outcomes Research Team.

作者信息

Donahue J G, Fuhlbrigge A L, Finkelstein J A, Fagan J, Livingston J M, Lozano P, Platt R, Weiss S T, Weiss K B

机构信息

Channing Laboratory, Department of Medicine, Brigham & Women's Hospital, Boston, MA, USA.

出版信息

J Allergy Clin Immunol. 2000 Dec;106(6):1108-14. doi: 10.1067/mai.2000.111432.

DOI:10.1067/mai.2000.111432
PMID:11112894
Abstract

BACKGROUND

Asthma is the most common chronic disease among children and the most frequent cause of hospitalization. Appropriate pharmacotherapy is a cornerstone of published national guidelines for the care of children with asthma.

OBJECTIVE

The goal was to compare the baseline pharmacotherapy and health care utilization from 1996 to 1997 in children with asthma at managed care organizations (MCOs).

METHODS

A common protocol was used to extract the study sample from 3 MCOs with automated claims and pharmacy databases. Children were selected if they were 3 to 15 years old as of June 1997 with 1 or more encounters (outpatient, emergency department visit, hospitalization) with an asthma diagnosis in the previous year.

RESULTS

Of the 13,352 children studied, less than 40% were given controllers during the 12-month interval, with ranges of 15% to 77% by level of bronchodilator use, 31% to 44% by age, and 38% to 42% by MCO. Among children given 6 or more bronchodilators, controller dispensing ranged from 73% to 89% among the 3 MCOs. Variability was most evident for inhaled corticosteroids, for which dispensing ranged from 51% to 70%. Rates of asthma hospitalization and emergency department visits also differed among the MCOs, ranging from 21 to 37 per 1000 person-years and 37 to 142 per 1000 person-years, respectively.

CONCLUSION

Five years after dissemination of national guidelines for care, the pattern of asthma therapy does not reflect guideline recommendations. Variation among health care organizations with respect to asthma therapy and utilization of health services exists. In addition, controller medications may not be used by all children who could benefit from them.

摘要

背景

哮喘是儿童中最常见的慢性病,也是住院的最常见原因。适当的药物治疗是已发布的国家儿童哮喘护理指南的基石。

目的

目的是比较1996年至1997年管理式医疗组织(MCO)中哮喘儿童的基线药物治疗和医疗保健利用情况。

方法

采用通用方案从3个拥有自动化理赔和药房数据库的MCO中提取研究样本。如果儿童截至1997年6月年龄在3至15岁之间,且上一年有1次或更多次(门诊、急诊科就诊、住院)哮喘诊断记录,则被选中。

结果

在研究的13352名儿童中,不到40%的儿童在12个月期间使用了控制药物,按支气管扩张剂使用水平计算,这一比例在15%至77%之间,按年龄计算在31%至44%之间,按MCO计算在38%至42%之间。在使用6次或更多次支气管扩张剂的儿童中,3个MCO中控制药物的配药率在73%至89%之间。吸入性糖皮质激素的差异最为明显,其配药率在51%至70%之间。MCO之间哮喘住院率和急诊科就诊率也有所不同,分别为每1000人年21至37次和每1000人年37至142次。

结论

在国家护理指南发布五年后,哮喘治疗模式并未反映指南建议。医疗保健组织在哮喘治疗和卫生服务利用方面存在差异。此外,并非所有可能受益的儿童都使用了控制药物。

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