De Simone R, Glombitza G, Vahl C F, Meinzer H P, Hagl S
University of Heidelberg and German Cancer Research Institute.
Am J Cardiol. 2000 Dec 15;86(12):1343-8. doi: 10.1016/s0002-9149(00)01239-x.
An improved perception of the magnitude and dynamics of intracardiac flow disturbances has been made possible by the advent of 3-dimensional (3-D) color Doppler, a new diagnostic procedure developed at our institution. This study describes the new insights derived from 3-D reconstruction of color Doppler flow patterns in patients with different heart valve diseases. The color Doppler flow data from 153 multiplanar transesophageal or transthoracic echocardiographic examinations has been obtained from 133 patients with heart valve disease; 73 patients had mitral regurgitation, 15 had mitral stenosis, 18 had aortic regurgitation, 26 had aortic stenosis, and 21 patients had tricuspid regurgitation. Four patients had pulmonary regurgitation associated with mitral valve disease. The 3-D reconstructions of color Doppler flow signals were accomplished by means of the "Heidelberg Raytracing model," developed at our institution. The 3-D color Doppler reconstructions were obtained in all patients. The 3-D images revealed for the first time the complex spatial distribution of the blood flow abnormalities in the heart chambers caused by different heart valve diseases. New patterns of intracardiac blood flow disturbances were observed and classified. Three-dimensional color Doppler provides a unique noninvasive method that can be easily applied for studying intracardiac blood flow disturbances in clinical practice.
我们机构开发的一种新的诊断程序——三维（3-D）彩色多普勒的出现，使人们对心内血流紊乱的程度和动态有了更好的认识。本研究描述了从不同心脏瓣膜疾病患者的彩色多普血流模式的三维重建中获得的新见解。对133例心脏瓣膜疾病患者进行了153次多平面经食管或经胸超声心动图检查，获取了彩色多普勒血流数据；73例患者有二尖瓣反流，15例有二尖瓣狭窄，18例有主动脉瓣反流，26例有主动脉瓣狭窄，21例有三尖瓣反流。4例患者有与二尖瓣疾病相关的肺动脉反流。彩色多普勒血流信号的三维重建是通过我们机构开发的“海德堡光线追踪模型”完成的。所有患者均获得了三维彩色多普勒重建图像。三维图像首次揭示了不同心脏瓣膜疾病引起的心腔内血流异常的复杂空间分布。观察并分类了心内血流紊乱的新模式。三维彩色多普勒提供了一种独特的非侵入性方法，可在临床实践中轻松应用于研究心内血流紊乱。
