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冠状动脉疾病患者中边缘性和未诊断糖尿病的临床影响。

Clinical impact of borderline and undiagnosed diabetes mellitus in patients with coronary artery disease.

作者信息

Tenenbaum A, Motro M, Fisman E Z, Boyko V, Mandelzweig L, Reicher-Reiss H, Graff E, Brunner D, Behar S

机构信息

Cardiac Rehabilitation Institute and the Bezafibrate Infarction Prevention Study Coordinating Center, Tel-Hashomer, Israel.

出版信息

Am J Cardiol. 2000 Dec 15;86(12):1363-6, A4-5. doi: 10.1016/s0002-9149(00)01244-3.

DOI:10.1016/s0002-9149(00)01244-3
PMID:11113414
Abstract

The present study was aimed to evaluate the prevalence and prognostic significance of unrecognized and newly defined borderline diabetes (with fasting blood sugar 126 to 139 mg/dl) by the American Diabetes Association criteria in coronary patients over a 7.7-year follow-up. Both undiagnosed and newly diagnosed borderline diabetes were associated with an unfavorable metabolic profile. The mortality of the borderline diabetics tended to be higher than in their nondiabetic counterparts. but this tendency did not reach statistical significance. A significant excess in long-term mortality was observed among the undiagnosed diabetes group.

摘要

本研究旨在通过美国糖尿病协会标准评估冠心病患者中未被识别的以及新定义的边缘性糖尿病(空腹血糖为126至139毫克/分升)的患病率及其在7.7年随访中的预后意义。未诊断出的和新诊断出的边缘性糖尿病均与不良代谢状况相关。边缘性糖尿病患者的死亡率往往高于非糖尿病患者,但这种趋势未达到统计学显著性。在未诊断出糖尿病的组中观察到长期死亡率显著过高。

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