阿替洛尔和普萘洛尔都会减弱运动引起的纤溶反应，但不会影响静息状态下的纤溶潜能。
Both atenolol and propranolol blunt the fibrinolytic response to exercise but not resting fibrinolytic potential.
作者信息
Fernhall B, Szymanski L M, Gorman P A, Kamimori G H, Kessler C M
机构信息
The Division of Cardiology, The George Washington University Medical Center, Washington, DC, USA.
出版信息
Am J Cardiol. 2000 Dec 15;86(12):1398-400, A6. doi: 10.1016/s0002-9149(00)01242-x.
Abstract
This randomized, double-blind trial found that tissue plasminogen activator activity increased and plasminogen activator inhibitor-1 activity decreased significantly more with exercise during placebo treatment than during treatment with beta blockade. These results suggest that beta blockade blunts the fibrinolytic response to maximal exercise.
摘要
这项随机双盲试验发现，与β受体阻滞剂治疗期间相比，安慰剂治疗期间运动后组织纤溶酶原激活物活性显著增加，纤溶酶原激活物抑制剂-1活性显著降低。这些结果表明，β受体阻滞剂会减弱最大运动时的纤溶反应。
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