Trindade L M, Rosenberg I L, Rozycki Z J, Giles G R
Br J Surg. 1975 Jan;62(1):11-4. doi: 10.1002/bjs.1800620104.
Measurements of the lower oesophageal sphincter pressure and gastric secretion were made in patients with dyspepsia but no reflux and in patients with a hiatus hernia and reflux in response to a near maximal dose of pentagastrin. Patients with hiatus hernia had lower resting sphincter pressures than those with dyspepsia. The magnitude of the pressure rise following pentagastrin was related to the resting tone of the sphincter. However, in terms of percentage increase over resting sphincteric pressure, patients with dyspepsia and patients with a hiatus hernia had similar response.
对消化不良但无反流的患者以及患有食管裂孔疝并伴有反流的患者，给予接近最大剂量的五肽胃泌素后，测量其食管下括约肌压力和胃液分泌情况。患有食管裂孔疝的患者其静息时括约肌压力低于消化不良患者。五肽胃泌素给药后压力上升的幅度与括约肌的静息张力有关。然而，就相对于静息括约肌压力的百分比增加值而言，消化不良患者和食管裂孔疝患者的反应相似。
