Pflücke F, Anders O, Mücke H
Dtsch Z Verdau Stoffwechselkr. 1981;41(5):234-40.
Between patients with reflux oesophagitis (n = 8), patients with symptoms of reflux without oesophagitis (n = 27) and controls (n = 17) recordings of lower oesophageal sphincter pressure have shown no significant differences of mean sphincter pressure but a significantly lower increase of mean sphincter pressure in patients with oesophagitis and/or symptoms of reflux after pentagastrin (6 microgram/Kg b.w., s.c.) by means of pull-through perfusionsmanometry. Nearly in half of the patients with oesophagitis and symptoms of reflux basal sphincter pressure and sphincter reaction on pentagastrin were found in a normal range. Disturbances of basal sphincter pressure and its reaction on pentagastrin have shown a dependence on the anamnesis duration.
在反流性食管炎患者（n = 8）、有反流症状但无食管炎的患者（n = 27）和对照组（n = 17）中，通过牵拉灌注测压法记录下食管括约肌压力，结果显示平均括约肌压力无显著差异，但在给予五肽胃泌素（6微克/千克体重，皮下注射）后，食管炎患者和/或有反流症状的患者平均括约肌压力的升高显著较低。近一半有食管炎和反流症状的患者，其基础括约肌压力和对五肽胃泌素的括约肌反应处于正常范围。基础括约肌压力及其对五肽胃泌素的反应障碍显示出与病史持续时间有关。
