来自寄生隐孢壳菌（Murr.）Barr菌株263细胞壁的免疫刺激剂（1→3）-D-葡聚糖。

Immunostimulant (1 --> 3)-D-glucans from the cell wall of Cryphonectria parasitica (Murr.) Barr strain 263.

作者信息

Molinaro A, Lanzetta R, Mancino A, Evidente A, Di Rosa M, Ianaro A

机构信息

Dipartimento di Chimica Organica e Biologica, Università di Napoli Federico II, Naples, Italy.

出版信息

Carbohydr Res. 2000 Nov 3;329(2):441-5. doi: 10.1016/s0008-6215(00)00178-6.

DOI:10.1016/s0008-6215(00)00178-6

PMID:11117327

Abstract

A (1 --> 3)-beta-D-glucan with approximately 30% of the residues having a beta-D-Glc-(1 --> 6) branch is the main water-soluble component of the cell wall polysaccharide of Cryphonectria parasitica (Murr.) Barr strain 263. A (1 --> 3)-glucan with both alpha and beta anomeric linkages was found in the water-insoluble polysaccharide fraction. Both fractions possess immunological activity, being able to induce the production of either tumour necrosis factor alpha (TNF-alpha) or nitrite (NO2-).

摘要

一种（1→3）-β-D-葡聚糖，约30%的残基带有β-D-葡萄糖-（1→6）分支，是寄生隐孢壳菌（Murr.）Barr菌株263细胞壁多糖的主要水溶性成分。在水不溶性多糖组分中发现了一种同时具有α和β异头键的（1→3）-葡聚糖。这两种组分都具有免疫活性，能够诱导肿瘤坏死因子α（TNF-α）或亚硝酸盐（NO2-）的产生。