Abraham S C, Ravich W J, Anhalt G J, Yardley J H, Wu T T
Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205-2196, USA.
Am J Surg Pathol. 2000 Dec;24(12):1678-82. doi: 10.1097/00000478-200012000-00014.
Involvement of the esophagus by lichen planus is a rarely reported condition. The histologic features of esophageal lichen planus, which may differ from those of cutaneous disease, have only rarely been illustrated. We describe a 58-year-old woman with skin and oral lichen planus who presented with dysphagia and an esophageal stricture that were ultimately diagnosed as esophageal lichen planus. Multiple esophageal biopsies demonstrated a lichenoid, T cell-rich lymphocytic infiltrate, along with degeneration of the basal epithelium and Civatte bodies. Correct diagnosis of esophageal lichen planus is critical because of its prognostic and therapeutic distinction from other more common causes of esophagitis and stricture formation.
扁平苔藓累及食管是一种鲜有报道的病症。食管扁平苔藓的组织学特征可能与皮肤病的特征有所不同,而相关报道极少。我们描述了一名58岁患有皮肤和口腔扁平苔藓的女性,她出现吞咽困难和食管狭窄,最终被诊断为食管扁平苔藓。多次食管活检显示为苔藓样、富含T细胞的淋巴细胞浸润,同时伴有基底上皮变性和西瓦特小体。正确诊断食管扁平苔藓至关重要,因为它在预后和治疗方面与其他更常见的食管炎和狭窄形成原因有所不同。