Merriman J E, Davies R O
Can Med Assoc J. 1975 Feb 22;112(4):447-51.
In a study of serum cholesterol and triglyceride concentrations in male physicians, blood was drawn after fasting from 2071 registrants at 17 Canadian medical meetings from 1968 to 1973. Eight regional medical laboratories participated in the study. About two thirds of the samples were analysed in one of two laboratories to diminish method variations. When chylomicronemia, hyperglycemia or extremely high triglyceride values were detected, suggesting nonfasting, the data were discarded. The mean serum cholesterol value for the total study population was 233.9 plus or minus 1.22 mg/dl and the mean serum triglyceride value, 150.5 plus or minus 2.48 mg/dl. The mean values and the prevalence of elevated values (cholesterol larger than or equal to 250 mg/dl; triglyceride larger than or equal to 150 mg/dl) were related to age. Of the total study population 34.7% had elevated cholesterol values and 36.2% had elevated triglyceride values; only the cholesterol value was elevated in 17.5%, only the triglyceride value in 19.6% and both values were elevated in 16.8%. Although this was not a random sampling of Canadian physicians or of Canadian men, our findings of elevated serum lipid values were similar to those in French Canadian civic workers, American executives and Scandinavians, and somewhat higher than those in the Albany, New York and Framingham populations, but distinctly higher than those reported by a recent Nutrition Canada survey.
在一项针对男性内科医生血清胆固醇和甘油三酯浓度的研究中，于1968年至1973年期间从17次加拿大医学会议的2071名注册人员中采集了空腹血液样本。八个地区医学实验室参与了该研究。约三分之二的样本在两个实验室之一进行分析，以减少方法差异。当检测到乳糜微粒血症、高血糖或极高的甘油三酯值，提示非空腹时，相关数据将被舍弃。整个研究人群的血清胆固醇平均值为233.9±1.22毫克/分升，血清甘油三酯平均值为150.5±2.48毫克/分升。平均值以及升高值的患病率（胆固醇大于或等于250毫克/分升；甘油三酯大于或等于150毫克/分升）与年龄相关。在整个研究人群中，34.7%的人胆固醇值升高，36.2%的人甘油三酯值升高；仅胆固醇值升高的占17.5%，仅甘油三酯值升高的占19.6%，两者均升高的占16.8%。尽管这并非对加拿大内科医生或加拿大男性的随机抽样，但我们关于血清脂质值升高的研究结果与法裔加拿大文职人员、美国企业高管和斯堪的纳维亚人的结果相似，略高于纽约州奥尔巴尼市和弗雷明汉人群的结果，但明显高于加拿大近期一项营养调查所报告的结果。
