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钆和利尿剂增强的磁共振尿路造影:与传统尿路造影在诊断输尿管梗阻原因方面的比较

Magnetic resonance urography enhanced by gadolinium and diuretics: a comparison with conventional urography in diagnosing the cause of ureteric obstruction.

作者信息

Jung P, Brauers A, Nolte-Ernsting C A, Jakse G, Günther R W

机构信息

Department of Urology, University of Technology, Aachen, Germany.

出版信息

BJU Int. 2000 Dec;86(9):960-5. doi: 10.1046/j.1464-410x.2000.00973.x.

Abstract

OBJECTIVE

To compare the ability of magnetic resonance urography (MRU), enhanced using gadolinium and frusemide diuresis, and conventional intravenous urography (IVU) to diagnose the cause of ureteric obstruction.

PATIENTS AND METHODS

The study included 82 patients in whom IVU showed or suggested obstruction and who also underwent MRU. The images from both methods were interpreted by various investigators independently; two evaluated the IVU and two others the MRU, the latter being unaware of the diagnosis after IVU. If the diagnosis remained unclear, further investigations (e.g. computed tomography, retrograde pyelography or ureteroscopy) were conducted.

RESULTS

The diagnoses were ureteric calculi in 72 patients, ureteric tumours in eight and extra-ureteric tumours in two. In those with urolithiasis, the diagnosis was correct with IVU in 49 patients and with MRU in 64. The diagnosis in this group was incorrect with MRU in only two patients. The main reason for the failure of IVU was absent contrast medium excretion. Three of eight patients with ureteric tumours were correctly diagnosed by IVU but in three patients the diagnosis was incorrect. MRU correctly diagnosed seven of the eight patients in this group, with no false diagnosis.

CONCLUSION

IVU is currently likely to remain the standard procedure for imaging the upper urinary tract, but this study shows the potential of MRU when enhanced with gadolinium and frusemide. MRU may be helpful if there is a dilated system with no excretory function, in pregnant women, in children and in those with contrast medium allergy.

摘要

目的

比较钆增强呋塞米利尿的磁共振尿路造影(MRU)与传统静脉尿路造影(IVU)诊断输尿管梗阻病因的能力。

患者与方法

该研究纳入了82例IVU显示或提示梗阻且接受了MRU检查的患者。两种检查方法的图像由不同的研究人员独立解读;两人评估IVU,另外两人评估MRU,后者不知道IVU后的诊断结果。如果诊断仍不明确,则进行进一步检查(如计算机断层扫描、逆行肾盂造影或输尿管镜检查)。

结果

诊断为输尿管结石的患者72例,输尿管肿瘤8例,输尿管外肿瘤2例。在尿路结石患者中,IVU诊断正确的有49例,MRU诊断正确的有64例。该组中MRU仅在2例患者中诊断错误。IVU诊断失败的主要原因是造影剂排泄缺失。8例输尿管肿瘤患者中有3例经IVU正确诊断,但有3例诊断错误。MRU正确诊断了该组8例患者中的7例,无假阳性诊断。

结论

IVU目前可能仍是上尿路成像的标准检查方法,但本研究显示了钆增强呋塞米的MRU的潜力。在存在无排泄功能的扩张系统的患者、孕妇、儿童以及对造影剂过敏的患者中,MRU可能会有帮助。

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