Department of Radiodiagnosis, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India.
Urology. 2013 Mar;81(3):623-7. doi: 10.1016/j.urology.2012.10.051. Epub 2013 Jan 3.
To assess the diagnostic accuracy of static magnetic resonance urography (MRU) in hydronephrosis and to compare parameters of hydronephrosis in MRU with intravenous urography (IVU).
Sixty-nine patients were included in this study of which 55 patients with a total of 63 hydronephrotic units underwent both IVU and MRU. MRU was performed on a 1.5 T scanner using heavily T2-weighted sequences. The level, grade, and cause of obstruction on each modality were interpreted by 2 radiologists. These were compared with the final diagnosis based on other appropriate modalities including imaging, intraoperative and histopathologic diagnosis.
The sensitivity and specificity MRU in detecting hydronephrosis were 95% and 100%, respectively. In determining the level of obstruction, the strength of agreement between IVU and MRU using kappa statistics was κ = 0.66, which corresponds to a good level of agreement. The Spearman correlation coefficient for the grade of hydronephrosis on MRU and IVU was 0.92 (95% confidence interval 0.86-0.95), with a P value of < .0001. The correct diagnosis was made in 89.2% of the cases by IVU and in 93.8% of the cases by MRU.
Along with a high sensitivity and specificity in detecting the presence, level, and grade of hydronephrosis, MRU without contrast also shows a good agreement with IVU. Static MRU can reliably replace IVU when the latter is contraindicated or technically difficult.
评估磁共振尿路成像(MRU)在肾积水诊断中的准确性,并比较 MRU 与静脉尿路造影(IVU)在肾积水参数上的差异。
本研究共纳入 69 例患者,其中 55 例患者共 63 个积水肾单位同时进行了 IVU 和 MRU 检查。MRU 在 1.5T 扫描仪上进行,采用重度 T2 加权序列。2 位放射科医生分别对两种检查方法的梗阻部位、程度和病因进行解读,并与基于其他适当检查方式(包括影像学、术中及组织病理学诊断)的最终诊断进行比较。
MRU 诊断肾积水的敏感性和特异性分别为 95%和 100%。在确定梗阻部位方面,κ 值为 0.66,IVU 和 MRU 之间的一致性较强。MRU 和 IVU 上肾积水程度的斯皮尔曼相关系数为 0.92(95%置信区间为 0.86-0.95),P 值<0.0001。IVU 正确诊断的病例占 89.2%,MRU 为 93.8%。
MRU 不仅在检测肾积水的存在、部位和程度方面具有较高的敏感性和特异性,而且与 IVU 具有良好的一致性,无需对比剂。在 IVU 禁忌或技术困难时,MRU 可作为可靠的替代方法。