Ayers J, Graves S A
Departments of Anesthesiology and Pediatrics, University of Florida College of Medicine, Gainesville, Florida, USA.
Paediatr Anaesth. 2001 Jan;11(1):41-4. doi: 10.1046/j.1460-9592.2001.00611.x.
Infants and children, particularly those who are chronically ill and maintained on total parenteral nutrition (TPN), are at risk for perioperative hypoglycaemia [blood glucose < 2.2 mmol x l(-1) (40 mg x dl(-1))] and hyperglycaemia [blood glucose > 11 mmol x l(-1) (200 mg x dl(-1))]. We surveyed paediatric anaesthesiologists regarding their perioperative management of blood glucose and TPN in paediatric patients to determine the current practice and its perceived success. Questionnaires were mailed to all members of the Study Group on Pediatric Anesthesia and the response rate was 70%. Results indicate that the current perioperative management of blood glucose and TPN is somewhat varied. Furthermore, greater than 10% of those surveyed report that their management results in a variable response in the maintenance of normoglycaemia. While the detrimental effects of perioperative hypoglycaemia and hyperglycaemia are rare, they are serious. A Medline search shows that no studies have been published regarding perioperative management of paediatric patients receiving TPN, although it appears that clinical study is warranted.
婴幼儿,尤其是那些患有慢性病且依靠全胃肠外营养(TPN)维持生命的患儿,围手术期存在低血糖[血糖<2.2 mmol/L(40 mg/dl)]和高血糖[血糖>11 mmol/L(200 mg/dl)]的风险。我们就儿科患者围手术期血糖及TPN的管理情况对儿科麻醉医生进行了调查,以确定当前的做法及其认为的成效。调查问卷邮寄给了小儿麻醉研究组的所有成员,回复率为70%。结果表明,目前围手术期血糖及TPN的管理方式有所不同。此外,超过10%的受访者表示,他们的管理在维持血糖正常方面效果不一。虽然围手术期低血糖和高血糖的不良影响很少见,但后果严重。一项医学文献检索显示,尚未有关于接受TPN的儿科患者围手术期管理的研究发表,不过似乎有必要进行临床研究。