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小儿日间手术中心的围手术期血糖:禁食和维持液的影响

Perioperative blood glucose in a paediatric daycase facility: effects of fasting and maintenance fluid.

作者信息

Adenekan Anthony Taiwo

机构信息

Department of Anaesthesia and Intensive Care, Faculty of Clinical Sciences, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria.

出版信息

Afr J Paediatr Surg. 2014 Oct-Dec;11(4):317-22. doi: 10.4103/0189-6725.143140.

Abstract

BACKGROUND

Many Children are daily exposed to prolonged preoperative fasting time. The choice of intraoperative maintenance fluid continues to be an issue of controversy. This study assesses the duration of preoperative fast among children undergoing ambulatory surgery and the appropriateness of the maintenance solutions used.

PATIENTS AND METHODS

Seventy-eight children undergoing ambulatory surgery were prospectively randomised to receive lactated Ringer's (LR) solution or 4.3% dextrose in 0.18% saline (DS) as maintenance fluid. The duration of preoperative fast was noted and the blood glucose measured at induction, but before infusion of any intravenous fluid, and subsequently every 30 min. Data were analysed with Statistical Packages for the Social Sciences 16.0 (SPSS incorporated, Chicago Ill, USA). P < 0.05 was considered as significant.

RESULTS

The age range was 3 months to 15 years (mean = 4.9 ± 3.6 years); mean weight was 16.3 ± 7.8 kg. The mean duration of fasting was 13.4 ± 3.5 h (range = 4-18.5 h), but no child was hypoglycaemic throughout the study. The mean blood glucose in the LR group rose steadily from 5.18 ± 0.98 mmol/L post-induction to a peak value of 7.40 mmol/L at 120 min. In the DS group, the mean blood glucose level increased from the post-induction value of 5.56 ± 0.86 mmol/L to 12.7 ± 3.98 mmol/L at 120 min.

CONCLUSION

Most children undergoing ambulatory surgery at our facility are still exposed to prolonged fasting time. Glucose containing fluid often administered as maintenance fluid to treat the presumed hypoglycaemia causes worsening hyperglycaemia, which may be harmful.

摘要

背景

许多儿童每天都面临术前长时间禁食的情况。术中维持液的选择仍然是一个有争议的问题。本研究评估了接受门诊手术儿童的术前禁食时间以及所用维持液的适宜性。

患者与方法

78例接受门诊手术的儿童被前瞻性随机分为两组,分别接受乳酸林格氏液(LR)或0.18%生理盐水加4.3%葡萄糖(DS)作为维持液。记录术前禁食时间,并在诱导时、输注任何静脉液体之前以及随后每30分钟测量一次血糖。数据采用社会科学统计软件包16.0(SPSS公司,美国伊利诺伊州芝加哥)进行分析。P<0.05被认为具有统计学意义。

结果

年龄范围为3个月至15岁(平均=4.9±3.6岁);平均体重为16.3±7.8kg。平均禁食时间为13.4±3.5小时(范围=4 - 18.5小时),但在整个研究过程中没有儿童出现低血糖。LR组的平均血糖从诱导后5.18±0.98mmol/L稳步上升至120分钟时的峰值7.40mmol/L。在DS组中,平均血糖水平从诱导后5.56±0.86mmol/L增加到120分钟时的12.7±3.98mmol/L。

结论

在我们机构接受门诊手术的大多数儿童仍然面临长时间禁食。通常作为维持液用于治疗假定低血糖的含糖液体导致高血糖恶化,这可能是有害的。

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