Iyoda A, Hiroshima K, Toyozaki T, Tsukamoto Y, Haga Y, Fujisawa T, Ohwada H
Division of Pathology, Chiba University School of Medicine, Chiba, Japan.
Pathol Int. 2000 Dec;50(12):979-83. doi: 10.1046/j.1440-1827.2000.01140.x.
Clear cell adenocarcinoma of the lung is extremely rare. On radiography, a 45-year-old female with fever was found to have an abnormal shadow in the left lower lung field. Bronchoscopy revealed a polypoid tumor in the left bronchus. On biopsy, the tumor was determined to be adenocarcinoma. Preoperative examination found no tumors outside of the lung. The patient underwent left lower lobectomy with bronchial wedge resection. The tumor had completely obstructed and dilated the left lower bronchus, but had not invaded the tissue outside the bronchial wall. Microscopically, the cytoplasm of the tumor cells contained abundant glycogen, and the tumor had solid and glandular structures. The tumor was diagnosed as clear cell adenocarcinoma of the lung.
肺透明细胞腺癌极为罕见。在影像学检查中，一名45岁发热女性被发现左下肺野有异常阴影。支气管镜检查显示左支气管有一个息肉样肿瘤。活检确定该肿瘤为腺癌。术前检查未发现肺部以外有肿瘤。患者接受了左下叶切除术及支气管楔形切除术。肿瘤已完全阻塞并扩张了左下支气管，但未侵犯支气管壁外的组织。显微镜下，肿瘤细胞的细胞质含有丰富的糖原，肿瘤具有实性和腺管状结构。该肿瘤被诊断为肺透明细胞腺癌。
