Tilak V, Jain R
Department of Pathology J.N. Medical College, Aligarh.
Indian J Pathol Microbiol. 1999 Oct;42(4):399-404.
The present study was conducted in the department of Haematology and Transfusion Medicine, Government Medical College & Hospital, Chandigarh over a period of 32 months. During this period pancytopenia was an indication for bone marrow (aspiration and or trephine) in 77 out of a total of 205 cases (37.6%). The most common cause of pancytopenia as revealed by bone marrow was megaloblastic anaemia (68%) followed by aplastic anaemia (7.70%). This study also revealed few uncommon and rare, but interesting causes of pancytopenia like drug induced agranulocytosis, hemophagocytic syndrome and waldenstroms macroglobinemia.
本研究在昌迪加尔政府医学院及医院的血液学与输血医学科进行,为期32个月。在此期间,在总共205例病例中,有77例(37.6%)因全血细胞减少而行骨髓(穿刺和/或活检)检查。骨髓检查显示,全血细胞减少最常见的原因是巨幼细胞贫血(68%),其次是再生障碍性贫血(7.70%)。本研究还揭示了一些全血细胞减少的罕见和不常见但有趣的原因,如药物性粒细胞缺乏症、噬血细胞综合征和华氏巨球蛋白血症。