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胫骨毛霉菌病:一例病例报告及文献综述

Mucormycosis of the tibia: a case report and review of the literature.

作者信息

Holtom P D, Obuch A B, Ahlmann E R, Shepherd L E, Patzakis M J

机构信息

LAC+USC Medical Center, Department of Orthopaedics, Los Angeles, CA, USA.

出版信息

Clin Orthop Relat Res. 2000 Dec(381):222-8.

Abstract

Mucormycosis is an uncommon but highly aggressive fungal infection most commonly occurring in hosts who are immunologically predisposed to infection. Only seven previously documented cases of tibial osteomyelitis attributable to Mucorales infection exist in the literature. An unusual case is reported of mucormycosis osteomyelitis developing in a patient who was immunocompromised after routine tibial Steinmann pin placement for the application of traction. Surgical debridement and amphotericin B were not sufficient to control the infection, and the patient subsequently underwent above-knee amputation. To the authors' knowledge this is the first description of mucormycosis causing osteomyelitis as a result of Steinmann pin tract infection.

摘要

毛霉病是一种罕见但极具侵袭性的真菌感染,最常发生于免疫功能易受感染的宿主。文献中仅有7例先前记录的由毛霉目感染引起的胫骨骨髓炎病例。本文报道了1例罕见病例,1名患者在常规置入胫骨斯氏针以施行牵引后出现免疫功能低下,进而发生毛霉病骨髓炎。手术清创和使用两性霉素B不足以控制感染,该患者随后接受了膝上截肢术。据作者所知,这是首次描述因斯氏针道感染导致毛霉病引发骨髓炎的病例。

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