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Phenylpropenamide derivatives as inhibitors of hepatitis B virus replication.

作者信息

Perni R B, Conway S C, Ladner S K, Zaifert K, Otto M J, King R W

机构信息

Avid Therapeutics, Inc., Philadelphia, PA 19104, USA.

出版信息

Bioorg Med Chem Lett. 2000 Dec 4;10(23):2687-90. doi: 10.1016/s0960-894x(00)00544-8.

DOI:10.1016/s0960-894x(00)00544-8
PMID:11128652
Abstract

A non-nucleoside class of compounds that inhibits the replication of hepatitis B virus (HBV) in cell culture has been discovered. A series of substituted analogues of phenylpropenamide 6 has been prepared and evaluated in the HepAD38 cellular assay. Structure-activity relationships of this series are discussed.

摘要

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