Pylkkö P, Lyytikäinen T, Ritola O, Pelkonen S
National Veterinary and Food Research Institute, Kuopio Regional Laboratory, Finland.
Dis Aquat Organ. 2000 Oct 25;43(1):77-80. doi: 10.3354/dao043077.
There is limited knowledge about the effects of oil-based vaccines on the growth of Arctic charr Salvelinus alpinus, in particular at different rearing temperatures. One-year-old Arctic charr were immunized intraperitoneally at 2.9 degrees C with a metabolizable oil-adjuvanted, bivalent vaccine containing killed typical and atypical Aeromonas salmonicida bacteria. After vaccination the non-vaccinated (controls) and vaccinated individually marked fish were held for 20 d at 10.0 degrees C and then for 7 wk at 10.3, 14.1 or 18.1 degrees C. During the first 20 d at 10.0 degrees C the growth rate (G) was higher for non-vaccinated than vaccinated fish. Thereafter vaccinated charr had higher G than control fish at 10.3 and 14.1 degrees C. In contrast, at 18.1 degrees C there was no difference in G and therefore no compensation of earlier growth suppression in vaccinated fish was observed at that temperature. The study indicates that vaccination has no ultimate negative effects on the growth of Arctic charr at temperatures ranging from 10.3 to 14.1 degrees C.
关于油基疫苗对北极红点鲑（Salvelinus alpinus）生长的影响，尤其是在不同养殖温度下的影响，目前所知有限。将一岁大的北极红点鲑在2.9摄氏度下腹腔注射一种含有可代谢油佐剂的二价疫苗，该疫苗包含灭活的典型和非典型杀鲑气单胞菌。接种疫苗后，未接种疫苗的（对照）和接种疫苗并单独标记的鱼先在10.0摄氏度下饲养20天，然后在10.3、14.1或18.1摄氏度下饲养7周。在10.0摄氏度下的前20天里，未接种疫苗的鱼的生长率（G）高于接种疫苗的鱼。此后，在10.3和14.1摄氏度下，接种疫苗的红点鲑的G高于对照鱼。相比之下，在18.1摄氏度下，G没有差异，因此在该温度下未观察到接种疫苗的鱼早期生长受抑制的情况得到补偿。该研究表明，在10.3至14.1摄氏度的温度范围内，接种疫苗对北极红点鲑的生长没有最终负面影响。
