Reddan D N, Szczech L A, Klassen P S, Owen W F
Duke Institute of Renal Outcomes Research and Health Policy, Division of Nephrology, Duke University Medical Center, Durham, North Carolina 27710, USA.
Semin Dial. 2000 Nov-Dec;13(6):399-403. doi: 10.1046/j.1525-139x.2000.00109.x.
The end-stage renal disease (ESRD) program has a significant overrepresentation of racial and ethnic minority groups. The increased susceptibility of nonwhite populations to ESRD has not been fully explained and probably represents a complex interplay of genetic, cultural, and environmental influences. Because the program delivers care under a uniform health care payment system, it represents a unique environment in which to explore variation in health care delivery. A number of disparities in outcomes and delivery of ESRD care have been noted for racial minority participants. These include possible overdiagnosis of hypertensive nephrosclerosis, decreased provision of renal replacement therapy, limited referral for home dialysis modalities, underprescription of dialysis, increased use of synthetic grafts rather than fistulas as permanent angioaccess, and delayed wait-listing for renal transplantation. Transplantation inequities mean that black patients are likely to remain on dialysis relatively longer, so that their susceptibility to less than optimal processes of care increases disproportionately. Improved survival and quality of life (QOL) for blacks with ESRD may have encouraged provider complacency about racial disparities in the ESRD program and in particular about referral for transplantation. It is also apparent that minority ESRD patients may, similar to their non-ESRD counterparts, be referred less frequently for invasive cardiovascular (CV) procedures. Despite these observations of inequality in ESRD care, the adjusted mortality for minority participants in the ESRD program are better than for the majority population. This seeming paradox may define an opportunity to improve outcomes for minorities with ESRD even more.
终末期肾病(ESRD)项目中种族和少数族裔群体的占比显著过高。非白人人群对ESRD易感性增加的原因尚未完全明确,可能是遗传、文化和环境因素复杂相互作用的结果。由于该项目在统一的医疗支付系统下提供护理,它代表了一个探索医疗服务差异的独特环境。已注意到少数族裔参与者在ESRD护理结果和服务方面存在一些差异。这些差异包括高血压性肾硬化可能存在过度诊断、肾脏替代治疗的提供减少、家庭透析方式的转诊受限、透析处方不足、作为永久性血管通路更多地使用合成移植物而非动静脉内瘘,以及肾移植等待名单延迟。移植不平等意味着黑人患者可能相对更长时间地接受透析,因此他们对低于最佳护理流程的易感性会不成比例地增加。ESRD黑人患者生存率和生活质量(QOL)的提高可能使医疗服务提供者对ESRD项目中的种族差异,特别是对移植转诊问题感到自满。同样明显的是,少数族裔ESRD患者可能与非ESRD患者一样,接受侵入性心血管(CV)手术的转诊频率较低。尽管观察到ESRD护理存在不平等现象,但ESRD项目中少数族裔参与者的校正死亡率优于大多数人群。这种看似矛盾的情况可能为进一步改善ESRD少数族裔患者的治疗结果带来契机。