Daskalakis G J, Mavrommatis K G, Moulopoulos G K, Diakomanolis E S, Michalas S S
First Department of Obstetrics and Gynecology, 'Alexandra' Maternity Hospital, Athens University, 80 Vas. Sophias Av., 115 28, Athens, Greece.
Eur J Obstet Gynecol Reprod Biol. 2001 Jan;94(1):149-51. doi: 10.1016/s0301-2115(00)00306-7.
Two unusual cases of a 22- and a 28-year-old woman, respectively, who were found to have endometrial adenocarcinoma, are presented. The patients experienced abnormal vaginal bleeding and the diagnosis was made by dilatation and curettage. They declined treatment with progestagens, therefore, a total abdominal hysterectomy, bilateral salpingo-oophorectomy and pelvic lymphadenectomy were performed in both cases. We emphasize the need of endometrial evaluation in young females with abnormal bleeding before starting any medical treatment. Specific problems of endometrial cancer at young age include delay in diagnosis, difficulty in pathologic interpretation of the curettings and the motivation of most patients to preserve their fertility.
本文报告了两例分别为22岁和28岁女性的不寻常病例,她们均被诊断为子宫内膜腺癌。患者出现异常阴道出血,诊断通过刮宫术确定。她们拒绝接受孕激素治疗,因此,两例患者均接受了全腹子宫切除术、双侧输卵管卵巢切除术和盆腔淋巴结清扫术。我们强调,在对任何年轻女性进行异常出血的治疗前,都需要进行子宫内膜评估。年轻女性子宫内膜癌的特殊问题包括诊断延迟、刮宫病理结果解释困难以及大多数患者保留生育功能的意愿。