抗坏血酸和α-生育酚对β-胡萝卜素抗氧化性的影响。

Effect of ascorbate and alpha-tocopherol on resistance of beta-carotene to oxidation.

作者信息

Kozachenko A I, Gurevich S M, Nagler L G

机构信息

Laboratory of Physical and Chemical Basis of Cell Metabolsim Control, NM Emanuel' Institute of Biochemical Physics, Russian Academy of Sciences, Moscow.

出版信息

Bull Exp Biol Med. 2000 Jul;130(7):661-4. doi: 10.1007/BF02682099.

DOI:10.1007/BF02682099

PMID:11140580

Abstract

The efficiency of ascorbate and alpha-tocopherol as stabilizers of beta-carotene, which is widely used in complex therapy and prevention of some diseases accompanied by oxidative stress, was studied. The latency of induced beta-carotene oxidation linearly depends on ascorbate concentration, while steady-state rate nonlinearly depends on the concentration of alpha-tocopherol, which attests to involvement of antioxidants in various stages of chain oxidation of beta-carotene.

摘要

研究了抗坏血酸盐和α-生育酚作为β-胡萝卜素稳定剂的效率，β-胡萝卜素广泛用于某些伴有氧化应激的疾病的综合治疗和预防。诱导的β-胡萝卜素氧化潜伏期与抗坏血酸盐浓度呈线性相关，而稳态速率与α-生育酚浓度呈非线性相关，这证明抗氧化剂参与了β-胡萝卜素链式氧化的各个阶段。