Moak J P, Moore H J, Lee S W, Giglia T M, Sable C A, Furbush N C, Ringel R R
Department of Cardiology, Children's National Medical Center, Washington, DC, USA.
J Interv Card Electrophysiol. 2000 Dec;4(4):621-31. doi: 10.1023/a:1026573816874.
Paroxysmal atrial fibrillation and atrial tachycardia may originate from a focal source in one or multiple pulmonary veins. A focal origin facilitates a potential cure amendable to radiofrequency ablation. Herein we report the case of a 16 year old adolescent male with a tachycardia induced cardiomyopathy who presented with very frequent paroxysmal episodes of atrial fibrillation, atrial flutter and atrial tachycardia. The origin of the arrhythmia was mapped to the secondary branches of the left lower pulmonary vein using an octapolar micro-mapping catheter. Immediately following application of three radiofrequency lesions, angiography of the left lower pulmonary vein revealed a region of focal stenosis at the site of energy application, with delayed pulmonary venous emptying. Attempts to relieve any element of spasm using direct administration of nitroglycerin were unsuccessful. Three months later repeat catheterization revealed an unchanged region of tight anatomical stenosis. Balloon dilation of two stenotic areas resulted in dramatic relief of the obstruction and improved venous drainage. Recatheterization 6 months later revealed mild restenosis that was successfully redilated. Intracardiac ultrasound demonstrated focal constriction. Care should be exercised in attempting RF ablation in distal arborization sites of the pulmonary veins in children, because of the small caliber compared to adult subjects. Radiofrequency induced focal areas of stenosis may be amenable to balloon catheter dilation.
阵发性心房颤动和房性心动过速可能起源于一条或多条肺静脉中的局灶性病灶。局灶性起源有利于通过射频消融实现潜在治愈。在此,我们报告一例16岁青少年男性病例,其患有心动过速性心肌病,表现为非常频繁的阵发性心房颤动、心房扑动和房性心动过速发作。使用八极微标测导管将心律失常的起源定位到左下肺静脉的二级分支。在施加三处射频消融损伤后,左下肺静脉血管造影显示在能量施加部位有局灶性狭窄区域,肺静脉排空延迟。直接给予硝酸甘油以缓解任何痉挛因素的尝试未成功。三个月后重复导管检查显示紧密解剖狭窄区域未改变。对两个狭窄区域进行球囊扩张导致梗阻显著缓解,静脉引流改善。6个月后再次导管检查显示轻度再狭窄,成功再次扩张。心内超声显示局灶性狭窄。由于与成人相比儿童肺静脉远端分支部位管径较小,因此在儿童肺静脉远端分支部位尝试进行射频消融时应谨慎操作。射频诱导的局灶性狭窄区域可能适合球囊导管扩张。