三种治疗环境下精神分裂症的抗精神病药物给药模式。

Antipsychotic dosing patterns for schizophrenia in three treatment settings.

作者信息

Remington G, Shammi C M, Sethna R, Lawrence R

机构信息

Department of Psychiatry, University of Toronto, Ontario, Canada.

出版信息

Psychiatr Serv. 2001 Jan;52(1):96-8. doi: 10.1176/appi.ps.52.1.96.

DOI:10.1176/appi.ps.52.1.96

PMID:11141536

Abstract

Daily dosages of antipsychotic medications were evaluated to determine whether current guidelines advocating lower dosing are being followed. A chart review of 163 outpatients with schizophrenia was undertaken in three outpatient hospital settings-a general community hospital, a provincial hospital, and an academic teaching hospital. The daily dosage in chlorpromazine equivalents was significantly higher in the provincial hospital (773.8 mg) than in the community hospital (355 mg) or the academic hospital (424.8 mg). A greater proportion of patients at the provincial hospital received conventional antipsychotics than novel antipsychotics or depot antipsychotics, and a greater proportion received more than one antipsychotic.

摘要

对抗精神病药物的每日剂量进行了评估，以确定当前倡导较低剂量的指南是否得到遵循。在三家门诊医院——一家普通社区医院、一家省级医院和一家学术教学医院，对163名精神分裂症门诊患者进行了病历审查。省级医院以氯丙嗪等效剂量计算的每日剂量（773.8毫克）显著高于社区医院（355毫克）或学术医院（424.8毫克）。省级医院接受传统抗精神病药物的患者比例高于新型抗精神病药物或长效抗精神病药物，且接受不止一种抗精神病药物的患者比例更高。