Xiao S, Ellwood S, Calis O, Patrick E, Li T, Coleman M, Turner J G
School of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, UK.
Science. 2001 Jan 5;291(5501):118-20. doi: 10.1126/science.291.5501.118.
Plant disease resistance (R) genes control the recognition of specific pathogens and activate subsequent defense responses. We show that the Arabidopsis thaliana locus RESISTANCE TO POWDERY MILDEW8 (RPW8) contains two naturally polymorphic, dominant R genes, RPW8.1 and RPW8.2, which individually control resistance to a broad range of powdery mildew pathogens. Although the predicted RPW8.1 and RPW8.2 proteins are different from the previously characterized R proteins, they induce localized, salicylic acid-dependent defenses similar to those induced by R genes that control specific resistance. Apparently, broad-spectrum resistance mediated by RPW8 uses the same mechanisms as specific resistance.
植物抗病（R）基因控制对特定病原体的识别并激活随后的防御反应。我们发现，拟南芥对白粉病8号抗性（RPW8）位点包含两个自然多态性的显性R基因，即RPW8.1和RPW8.2，它们各自控制对多种白粉病病原体的抗性。尽管预测的RPW8.1和RPW8.2蛋白与先前鉴定的R蛋白不同，但它们诱导的局部水杨酸依赖性防御与控制特异性抗性的R基因所诱导的防御相似。显然，由RPW8介导的广谱抗性与特异性抗性使用相同的机制。
