Yamamoto N
Dept. of Internal Medicine IV, Kinki University School of Medicine, 377-2 Ohno-higashi, Oosaka-Sayama 589-8511, Japan.
Gan To Kagaku Ryoho. 2000 Dec;27(14):2267-74.
There are no guidelines for dose escalation methods of combination chemotherapy. Thus, in order to evaluate this method, we selected 30 reports on two drug combination chemotherapies without support by BMT, that were published in the Journal of Clinical Oncology from 1997 to 1999. The present report describes the starting dose, patient number at each dose level, or dose escalation method in these 30 papers.
联合化疗的剂量递增方法尚无指南。因此，为了评估该方法，我们选取了1997年至1999年发表在《临床肿瘤学杂志》上的30篇关于两种药物联合化疗且无骨髓移植支持的报告。本报告描述了这30篇论文中的起始剂量、各剂量水平的患者数量或剂量递增方法。
