三环类抗抑郁药、苯二氮䓬类药物和抗精神病药物联合中毒后成功进行长时间心肺复苏。

Successful prolonged cardiopulmonary resuscitation after a combined intoxication with a tricyclic antidepressant, a benzodiazepine and a neuroleptic.

作者信息

Christiaens F, Lessire H, Dellers I, Denis B, Vankeerberghen L, Verborgh C

机构信息

Department of Critical Care, University Hospital, Vrije Universiteit Brussel, Brussels, Belgium.

出版信息

Eur J Emerg Med. 2000 Sep;7(3):229-36. doi: 10.1097/00063110-200009000-00011.

DOI:10.1097/00063110-200009000-00011

PMID:11142276

Abstract

We report the case of a patient who co-ingested a tricyclic antidepressant (amitriptyline), benzodiazepines (alprazolam and lormetazepam) and a neuroleptic drug (prothipendyl). Major neurologic and cardiac symptoms occurred including a prolonged cardiac arrest. The cardiopulmonary resuscitation phase was complicated by a haematoma of the liver treated by a left hepatectomy. The clinical features and management of this combined intoxication are discussed.

摘要

我们报告了一例同时摄入三环类抗抑郁药（阿米替林）、苯二氮䓬类药物（阿普唑仑和氯美扎酮）及抗精神病药物（丙酰奋乃静）的患者。出现了严重的神经和心脏症状，包括长时间心脏骤停。心肺复苏阶段因肝血肿而复杂化，最终通过左肝切除术进行治疗。本文讨论了这种混合中毒的临床特征及处理方法。