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[阿米替林中毒后的复苏]

[Resuscitation after intoxication with amitriptylin].

作者信息

Fippel A, Berkel H, Finkemeyer S, Knape R, Hoitz J

机构信息

Abteilung X, Bundeswehrkrankenhauses Hamburg.

出版信息

Anasthesiol Intensivmed Notfallmed Schmerzther. 2005 Sep;40(9):544-8. doi: 10.1055/s-2005-870204.

Abstract

Intoxications with tricyclic antidepressants are often life threatening situations. In consequence of interference with many organ systems specific treatment consists in transportation to hospital under cardiopulmonary monitoring by physicians. The multiple possibilities of complications require the following treatments: continuous monitoring of the cardiovascular system, gastrolavage, application of carbon through a nasogastric tube, intubation and controlled ventilation in case of coma and continuous stand by for defibrillation. Additionally patients with stable parameters should be monitored in intensive care units because often there are no precursors of cardiac or pulmonary complications. We report the case of a 49-year old women with ingestion of 2500 mg of amitriptyline who suffered from multiple cardiac arrhythmias with following cardiac arrests and who required multiple defibrillations and resuscitation.

摘要

三环类抗抑郁药中毒常常危及生命。由于其会干扰多个器官系统,具体治疗措施包括在医生进行心肺监测的情况下送往医院。并发症的多种可能性需要以下治疗:持续监测心血管系统、洗胃、通过鼻胃管给予活性炭、昏迷时进行插管和控制通气以及持续准备除颤。此外,参数稳定的患者应在重症监护病房进行监测,因为心脏或肺部并发症往往没有先兆。我们报告了一例49岁女性摄入2500毫克阿米替林的病例,该患者出现多种心律失常,随后心脏骤停,需要多次除颤和复苏。

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